China Origin Retatrutide 10mg/15mg/20mg/30mg Lyophilized Powder For The Treatment Of Type 2 Diabetes And Weight Control

Product Name: Retatrutide Lyophilized Powder CAS No.: 2381089-83-2 Molecular Formula: C221H342N46O68 Molecular Weight: 4730.91 Purity: ≥99.0% Dosages: Retatrutide 5mg; Retatrutide 10mg; Retatrutide 15mg; Retatrutide 20mg; Retatrutide 30mg.

Description:

Product Name: Retatrutide Lyophilized Powder

CAS No.: 2381089-83-2

Molecular Formula: C221H342N46O68

Molecular Weight: 4730.91

Purity: ≥99.0%

Dosages: Retatrutide 5mg; Retatrutide 10mg; Retatrutide 15mg; Retatrutide 20mg; Retatrutide 30mg.

Brief Introduction:

Retatrutide is an active compound released by Eli Lilly in June 2023. It is a triple (GLP-1/GIP/Gcg) agonist based on the GLP/GI dual receptor agonist Tirzepatide through a hybrid glucagon (GlucagonGcg) related structure, and is a drug for the treatment of obesity and type 2 diabetes. This active compound can activate receptor agonists in our body, which helps control blood sugar and weight loss management.

 

Sequence:

H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

 

Mechanism of Action:

Retatrutide achieves comprehensive metabolic regulation through triple receptor activation:

※ GLP-1R: Slows gastric emptying, enhances satiety, and reduces appetite.

※ GIPR: Regulates hunger signals in the central nervous system, further suppresses appetite and improves energy metabolism.

※ GCGR: Promotes glucagon secretion, accelerates fat and glycogenolysis, and increases basal metabolic rate.

 

Indications and Efficacy:

★ Obesity Treatment:

In the Phase II clinical trial, patients in the highest dose group (12 mg) lost an average of 24.2% weight after 48 weeks, and some patients lost more than 30%.

★ Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD):

Retatrutide can reduce liver fat content by 86%, and more than 85% of patients achieve regression of liver steatosis.

★ Type 2 Diabetes:

Significantly reduce glycated hemoglobin (HbA1c) and improve blood sugar control.

★ Potential Cardiovascular Benefits:

Animal studies have shown that it may indirectly protect cardiovascular health by improving blood pressure and heart function, but further clinical verification is needed.

 

Product Display:

Storage Conditions:

Preserved in air tight containers, protected from light (Recommended Temperature: -25℃ ~ -15℃).

 

Shelf Life:

24 months from the date of manufacturing when stored under the above conditions.

 

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