Product Name: Retatrutide Lyophilized Powder CAS No.: 2381089-83-2 Molecular Formula: C221H342N46O68 Molecular Weight: 4730.91 Purity: ≥99.0% Dosages: Retatrutide 5mg; Retatrutide 10mg; Retatrutide 15mg; Retatrutide 20mg; Retatrutide 30mg.
Product Name: Retatrutide Lyophilized Powder
CAS No.: 2381089-83-2
Molecular Formula: C221H342N46O68
Molecular Weight: 4730.91
Purity: ≥99.0%
Dosages: Retatrutide 5mg; Retatrutide 10mg; Retatrutide 15mg; Retatrutide 20mg; Retatrutide 30mg.
Brief Introduction:
Retatrutide is an active compound released by Eli Lilly in June 2023. It is a triple (GLP-1/GIP/Gcg) agonist based on the GLP/GI dual receptor agonist Tirzepatide through a hybrid glucagon (GlucagonGcg) related structure, and is a drug for the treatment of obesity and type 2 diabetes. This active compound can activate receptor agonists in our body, which helps control blood sugar and weight loss management.
Sequence:
H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
Mechanism of Action:
Retatrutide achieves comprehensive metabolic regulation through triple receptor activation:
※ GLP-1R: Slows gastric emptying, enhances satiety, and reduces appetite.
※ GIPR: Regulates hunger signals in the central nervous system, further suppresses appetite and improves energy metabolism.
※ GCGR: Promotes glucagon secretion, accelerates fat and glycogenolysis, and increases basal metabolic rate.
Indications and Efficacy:
★ Obesity Treatment:
In the Phase II clinical trial, patients in the highest dose group (12 mg) lost an average of 24.2% weight after 48 weeks, and some patients lost more than 30%.
★ Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD):
Retatrutide can reduce liver fat content by 86%, and more than 85% of patients achieve regression of liver steatosis.
★ Type 2 Diabetes:
Significantly reduce glycated hemoglobin (HbA1c) and improve blood sugar control.
★ Potential Cardiovascular Benefits:
Animal studies have shown that it may indirectly protect cardiovascular health by improving blood pressure and heart function, but further clinical verification is needed.
Product Display:
Storage Conditions:
Preserved in air tight containers, protected from light (Recommended Temperature: -25℃ ~ -15℃).
Shelf Life:
24 months from the date of manufacturing when stored under the above conditions.
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